This page is reference information only. Most compounds described here are research chemicals, not FDA-approved medications. MyTRT does not sell, recommend, or endorse the use of these substances. Always consult a qualified physician.
Arimidex (Anastrozole)
Aromatase Inhibitor (AI)
/WHAT_IT_IS
Arimidex (anastrozole) is a non-steroidal aromatase inhibitor that blocks the conversion of androgens into estrogen, reducing estrogen levels in the body.
/USAGE
Used clinically to treat hormone receptor‑positive breast cancer in postmenopausal women; off-label in men and bodybuilders for estrogen management, gynecomastia prevention, and testosterone therapy.
/MECHANISM_OF_ACTION
Reversibly inhibits aromatase enzyme, preventing the aromatization of testosterone and androstenedione into estradiol and estrone.
Reported Benefits
- +Reduces estrogen levels
- +Helps prevent gynecomastia
- +Supports hormonal balance during TRT or steroid cycles
- +Used in breast cancer treatment and prevention
Reported Side Effects
- −Hot flashes
- −Joint/muscle pain and stiffness
- −Fatigue or weakness
- −Bone mineral density reduction (osteopenia/osteoporosis)
- −Nausea
- −Rare allergic reactions or liver enzyme changes
/STACKED_WITH
/RESEARCH_NOTES
Therapeutic dose of 1 mg/day yields ~97% aromatase inhibition; hepatic metabolism accounts for ~85% of elimination, excreted primarily via urine and feces. Noted off-label use in men for estrogen control :contentReference[oaicite:1]{index=1}.
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