This page is reference information only. Most compounds described here are research chemicals, not FDA-approved medications. MyTRT does not sell, recommend, or endorse the use of these substances. Always consult a qualified physician.
HMG (Human Menopausal Gonadotropin)
Gonadotropin (FSH/LH blend)
/WHAT_IT_IS
HMG, also called menotropins, provides both follicle-stimulating hormone (FSH) and luteinizing hormone (LH) bioactivity. In research settings, it’s used to study gametogenesis and steroidogenesis by directly stimulating gonadal FSHR and LHCGR pathways.
/USAGE
Investigated for inducing follicular development, supporting spermatogenesis, and modeling endocrine feedback in the hypothalamic–pituitary–gonadal (HPG) axis.
/MECHANISM_OF_ACTION
FSH component activates FSH receptors in gonadal tissue to promote follicular growth and Sertoli-cell–mediated spermatogenesis. LH component activates LH/CG receptors to stimulate theca/Leydig cell steroidogenesis (estradiol/testosterone).
Reported Benefits
- +Stimulates follicular development (ovary)
- +Supports spermatogenesis (testis)
- +Increases gonadal steroid production
- +Useful for HPG-axis functional studies
Reported Side Effects
- −Injection-site pain or redness
- −Abdominal discomfort/bloating
- −Headache or mood changes
- −Fluid retention
- −Gynecomastia (males)
- −Ovarian hyperstimulation–like effects in susceptible models
/STACKED_WITH
/RESEARCH_NOTES
Potency and LH bioactivity vary by preparation; many modern lots derive LH activity via hCG content. Monitoring estradiol/testosterone and ultrasound/gonadal metrics is common in controlled studies.
/RELATED
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