/DISCLAIMER · RESEARCH_COMPOUND

This page is reference information only. Most compounds described here are research chemicals, not FDA-approved medications. MyTRT does not sell, recommend, or endorse the use of these substances. Always consult a qualified physician.

/MOTS_C_10MG
Peptide

MOTS C

Mitochondrial-Derived Peptide

/HALF_LIFE
Approx. 2–3 hours
/DELIVERY
Subcutaneous injection

/WHAT_IT_IS

MOTS-c is a peptide encoded by mitochondrial DNA, involved in metabolic regulation, cellular protection, and potentially anti-aging effects.

/USAGE

Studied for its role in metabolic health, mitochondrial function, and physical endurance enhancement.

/MECHANISM_OF_ACTION

Activates AMPK signaling and regulates mitochondrial respiration to improve insulin sensitivity and reduce oxidative stress.

Reported Benefits

  • +Improved insulin sensitivity
  • +Enhanced energy metabolism
  • +Increased endurance

Reported Side Effects

  • Temporary fatigue
  • Minor site irritation
  • Mild nausea (rare)

/STACKED_WITH

AOD-9604GHK-CuMetformin (in metabolic studies)

/RESEARCH_NOTES

Exciting area of longevity and metabolic health research; interest growing for its gene-regulating potential.

/REFERENCE

https://pubmed.ncbi.nlm.nih.gov/36761202/

/RELATED

/TRACK_THIS

Browse all 89 in the app.

MyTRT's in-app library has the same 89 peptide entries plus dosing notes, stack builders, and the ability to log them alongside your TRT protocol.

Last reviewed: 2026-06-04 · Reference only. Not medical advice. Consult a qualified physician.