/DISCLAIMER · RESEARCH_COMPOUND

This page is reference information only. Most compounds described here are research chemicals, not FDA-approved medications. MyTRT does not sell, recommend, or endorse the use of these substances. Always consult a qualified physician.

/NSI_189_PHOSPHATE_20MG
Peptide

NSI-189 Phosphate

Neurogenic Research Compound

/HALF_LIFE
17–20 hours
/DELIVERY
Oral

/WHAT_IT_IS

NSI-189 is a neurogenic compound developed to stimulate neurogenesis in the hippocampus and has been studied for depression and cognitive impairment.

/USAGE

Investigated for its potential in treating major depressive disorder (MDD) and cognitive decline. Also explored for stroke recovery.

/MECHANISM_OF_ACTION

Stimulates neurogenesis and increases hippocampal volume. May modulate BDNF and other neurotrophic pathways.

Reported Benefits

  • +Mood elevation
  • +Cognitive support
  • +Potential neurogenesis

Reported Side Effects

  • Mild headaches
  • Fatigue
  • GI discomfort (rare)

/STACKED_WITH

Lion’s ManeNoopeptOmega-3 fatty acids

/RESEARCH_NOTES

Demonstrated improvements in depression symptoms and cognitive performance in early-stage clinical trials.

/TRACK_THIS

Browse all 89 in the app.

MyTRT's in-app library has the same 89 peptide entries plus dosing notes, stack builders, and the ability to log them alongside your TRT protocol.

Last reviewed: 2026-06-04 · Reference only. Not medical advice. Consult a qualified physician.