This page is reference information only. Most compounds described here are research chemicals, not FDA-approved medications. MyTRT does not sell, recommend, or endorse the use of these substances. Always consult a qualified physician.
SS-31
Mitochondria-Targeted Peptide
/WHAT_IT_IS
SS-31 (also known as Elamipretide or Bendavia) is a synthetic tetrapeptide that selectively targets cardiolipin on the inner mitochondrial membrane to improve mitochondrial function and reduce oxidative stress.
/USAGE
Used in research on mitochondrial dysfunction, ischemia-reperfusion injury, heart failure, neurodegenerative diseases, and age-related decline in bioenergetics.
/MECHANISM_OF_ACTION
Binds to cardiolipin in the inner mitochondrial membrane, stabilizing cristae structure, enhancing electron transport chain efficiency, reducing reactive oxygen species production, and preventing cytochrome c peroxidase activity.
Reported Benefits
- +Improved mitochondrial bioenergetics
- +Reduced reactive oxygen species (ROS) production
- +Protection against ischemia-reperfusion injury
- +Improved cardiac and skeletal muscle function
- +Neuroprotective effects in models of neurodegeneration
Reported Side Effects
- −Injection-site reactions
- −Nausea
- −Headache
- −Possible mild hypotension
/STACKED_WITH
/RESEARCH_NOTES
Demonstrated safety and efficacy in preclinical models and early-phase clinical trials for heart failure and mitochondrial myopathy; improves mitochondrial structure and function across multiple tissues.
/REFERENCE
https://pubmed.ncbi.nlm.nih.gov/23005736/Browse all 89 in the app.
MyTRT's in-app library has the same 89 peptide entries plus dosing notes, stack builders, and the ability to log them alongside your TRT protocol.