This page is reference information only. Most compounds described here are research chemicals, not FDA-approved medications. MyTRT does not sell, recommend, or endorse the use of these substances. Always consult a qualified physician.
Tamoxifen (Nolvadex)
Selective Estrogen Receptor Modulator (SERM)
/WHAT_IT_IS
Tamoxifen, sold as Nolvadex, is a non-steroidal SERM that blocks estrogen action in breast tissue while acting as a partial agonist in other tissues.
/USAGE
Used clinically to treat and prevent estrogen receptor-positive breast cancer, off-label for gynecomastia prevention, and in post-cycle therapy to restore hormones.
/MECHANISM_OF_ACTION
Binds to estrogen receptors in target tissues, antagonizing estrogen in breast tissue, while acting agonistically in bone/endometrium.
Reported Benefits
- +Prevents recurrence of ER+ breast cancer
- +Reduces risk of contralateral breast cancer
- +Supports fertility and HPTA restoration in men
- +Treats and prevents gynecomastia
Reported Side Effects
- −Hot flashes
- −Vaginal discharge or bleeding
- −Increased risk of endometrial cancer
- −Blood clots (DVT/PE)
- −Cataracts or changes in vision
- −Mood changes, headaches
/STACKED_WITH
/RESEARCH_NOTES
Long-used standard for ER+ breast cancer therapy and prevention; non-supplemental status in PCT. Promotes fertility support via GnRH/LH/FSH axis modulation.
/RELATED
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