/WHAT_IT_IS
Transferrin saturation = iron ÷ TIBC × 100. The most useful single marker for distinguishing iron deficiency from chronic disease.
/NORMAL_RANGE
Reference: 20–50%. <20% = likely iron deficiency. >45% = consider hemochromatosis screening.
What does high TSAT mean?
- +Hemochromatosis, hemolysis.
What does low TSAT mean?
- +Iron deficiency, chronic inflammation.
/ON_TRT
TSAT >45% combined with high ferritin warrants genetic testing for HFE mutations (hemochromatosis), especially in men of Northern European descent.
/RELATED
/TRACK_THIS
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